back to indexRichard B. Dewey, Jr. | "The Neurologic Healings of Jesus" | Math3ma Symposium 2024
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I was so honored to receive the invitation to speak to this group. 00:00:15.840 |
And I will say I appreciate all of the effort that she went to. 00:00:20.160 |
I've never had as many helpful emails in preparation for this as I had from her. 00:00:30.120 |
I don't normally, when I give a talk, like to talk about my personal background, but 00:00:35.000 |
I don't know most of you here, and most importantly, Tai-Danae instructed me to do this. 00:00:40.520 |
So I will go over this very briefly, just by way of introduction. 00:00:45.360 |
I had the pleasure of being raised in a Christian home. 00:00:49.360 |
Both of my parents were believers at the time of my birth, and so I had that huge advantage. 00:00:55.880 |
But I was also, as a youngster, fascinated by the natural world. 00:01:00.580 |
And every summer, you could find me out in the yard with a butterfly net, capturing every 00:01:06.480 |
conceivable insect I could find and studying those. 00:01:10.940 |
Eventually, I grew up, went to college at Duke University with a degree in biology. 00:01:18.120 |
Most significant thing that happened to me during that time was I met my future wife. 00:01:25.160 |
And then I went to medical school, Baylor College of Medicine in Houston. 00:01:30.800 |
I was actually born in Houston, so I was back home for that phase of my life. 00:01:36.240 |
And I actually got married to Debbie during my final year of training in medical school 00:01:43.920 |
And if you've ever spent any time in Texas, you'll know, unlike Southern California, it 00:01:51.120 |
In fact, it's one of the hottest places in the country during the summer. 00:01:56.480 |
And so what I decided to do was move to the coldest place in the country. 00:02:01.760 |
And I did my neurology training and ultimately a fellowship in movement disorders at Mayo 00:02:11.320 |
My final year there was a combined fellowship in movement disorders where I did about three-fourths 00:02:18.840 |
of it there in Rochester, but during the winter, I was able to rotate to their Scottsdale, 00:02:26.840 |
And that was fulfilling a promise I made to Debbie that I would only make her spend three 00:02:38.760 |
Following that, my first job was actually my faculty position at University of Texas 00:02:47.160 |
I joined that as a brand new assistant professor and stayed there for almost 30 years, gradually 00:02:56.440 |
And I'll tell you a little bit more in just a minute about my research interest there. 00:03:02.480 |
And then very recently, just in January of '23, so just a year and a half ago, I retired 00:03:09.440 |
from that position and moved to a small boutique practice on the beach in Florida. 00:03:16.960 |
There are a number of reasons why I decided to do that. 00:03:20.440 |
The most important was my eldest son, who is also a physician, and although I told him, 00:03:26.640 |
"Hey, we need a cardiologist, a gastroenterologist," something like that in the family, instead 00:03:33.160 |
he went into neurology and movement disorders. 00:03:36.780 |
So he does exactly what I do, and he took this job in Florida with a longstanding friend 00:03:42.780 |
of mine, and when he got there, he started calling me up and saying, "Dad, why are you 00:03:47.880 |
still practicing in Dallas when you could join us here in Florida?" 00:03:53.360 |
And eventually they twisted my arm and we decided to do that. 00:03:58.240 |
Also I had always harbored a lifelong dream of retiring in Florida, which is kind of a 00:04:05.040 |
funny story there because when I mentioned this to my wife, she said, "Well, you've never 00:04:11.360 |
So that was something we learned about each other late in the course of our relationship. 00:04:18.240 |
Most importantly, though, I do want to share with you a little bit about my spiritual development. 00:04:22.320 |
I already told you I was born into a Christian family. 00:04:26.340 |
My parents nurtured me and the Lord from the earliest age. 00:04:29.840 |
Some of my earliest memories are sitting on the side of my bed before sleep and being 00:04:36.840 |
read to by my mom and dad from the Bible in pictures in little eyes. 00:04:42.240 |
And very early on, I understood the gospel as a child would understand it and received 00:04:51.640 |
I also had the privilege of being raised in a number of different Bible-believing churches 00:04:59.680 |
My dad was very interested in small group fellowship type of activities, and he really 00:05:08.880 |
And so starting probably even in junior high, I began to look for opportunities to be involved 00:05:15.860 |
in home fellowship groups and was given some leadership roles in that, and really that 00:05:26.560 |
In college, I discovered the tape ministry of John MacArthur. 00:05:30.840 |
And back in those days, there were no MP3s, nothing you could download, so I had a huge 00:05:35.680 |
drawer full of those tapes that I was listening through. 00:05:40.280 |
And that was a huge element in my spiritual development. 00:05:44.920 |
Ultimately, as I grew older, with the church that I was involved with, I had the opportunity 00:05:51.200 |
to kind of head up a home fellowship ministry there at the church and was tasked with writing 00:05:58.000 |
kind of an advanced Bible study series on 14 books of the Bible. 00:06:03.920 |
And that just consisted of questions that kind of elucidated what the text was talking 00:06:09.880 |
about and led to discussion and sharing about how the Lord was working our lives. 00:06:16.440 |
Ultimately, I was asked to serve as an elder, where I did, at Countryside Bible Church, 00:06:23.240 |
That's where we lived for almost those 30 years when I was in Dallas. 00:06:28.960 |
And then I had the additional privilege of being asked to serve as a member of the board 00:06:33.160 |
of directors of Master's Seminary and University from 2016 to 2021. 00:06:39.600 |
As you can tell from those dates, towards the latter part there, we had some real difficult 00:06:45.640 |
times trying to figure out how do you navigate a worldwide pandemic in a state that really 00:06:51.800 |
wants to shut you down if you're a Christian. 00:06:55.080 |
And so the Lord worked really amazingly in my life and I think in the lives of all of 00:07:07.600 |
My primary passion from the very beginning has been the field of Parkinson's disease. 00:07:14.560 |
Someone asked me earlier, "Why did you go into Parkinson's? 00:07:19.360 |
Interestingly, I had no one in the family, so it wasn't a personal thing. 00:07:24.080 |
But as I was going through my neurology training, I was particularly drawn to this disease. 00:07:29.200 |
I think mainly because of its therapeutic emphasis. 00:07:34.400 |
Neurology sometimes carries kind of a bad rap that we make a lot of diagnoses, but we 00:07:43.800 |
That is becoming less and less true, but at the time I was going through it, we looked 00:07:48.520 |
at Parkinson's as one of the most therapeutic of the different diseases that we saw. 00:07:53.880 |
And so that drew me, I think, into the field. 00:07:57.600 |
A little bit about Parkinson's, for those of you that aren't familiar with it, this 00:08:07.080 |
We've known about it ever since 1817, which was the first original description of the 00:08:14.120 |
But it's fascinating, if you travel to India and examine some of the cave drawings that 00:08:20.160 |
date back to 5,000 years BC, you can find etchings in caves that look all the world 00:08:26.920 |
like they're depicting patients with Parkinson's disease. 00:08:29.800 |
So we think this has been a problem with humans since the beginning, although we've known 00:08:34.680 |
very little about it until the last 200 years. 00:08:38.680 |
The biggest problem with Parkinson's is that it is an inexorable brain disease. 00:08:44.920 |
Once the problem begins, it progresses inexorably. 00:08:49.560 |
And we now know that the primary problem is the deposition of an otherwise normal brain 00:08:55.480 |
protein that begins to undergo a conformational change. 00:09:00.240 |
And in oligomers, which are small clumps of that protein, they're toxic to the brain cells. 00:09:08.080 |
And what they essentially do, as best we can tell, is these oligomers of alpha-synuclein 00:09:17.320 |
And mitochondria, as you know, are the energy pumps of every living cell. 00:09:22.360 |
And if you damage those mitochondria, eventually the cell begins to die, and ultimately energy 00:09:30.960 |
And so I developed very early on in my academic career an interest in figuring out a way to 00:09:37.160 |
slow or stop the progression of Parkinson's disease. 00:09:40.520 |
And that was really the primary effort that I employed while I was there for those 30 00:09:49.000 |
And I just want to show you an example of this, just for those of you that aren't familiar 00:09:54.440 |
What this represents is a cut section of the human midbrain, which is the part of the brain 00:10:00.280 |
way in the back of the head, just above the spinal cord. 00:10:04.720 |
And what you can see in a normal person, and this incidentally does not involve any stains, 00:10:10.120 |
this is visible to the naked eye, you see these very dark bands that are present in 00:10:18.160 |
If you look at your Parkinson's disease brain, what you can see from the back of the room 00:10:25.940 |
And the reason they've disappeared is shown here. 00:10:29.480 |
This is the normal cut section through one of those black lines. 00:10:33.180 |
You see all those large cell bodies of neurons. 00:10:36.940 |
And in the Parkinson's disease brain, those neurons have disappeared. 00:10:41.020 |
So this is disease in which the neurons that live in this area begin to degenerate. 00:10:47.840 |
And this little animation here at the bottom, what I'm just showing you is that this is 00:10:52.840 |
now recognized as what we call a dying back axonopathy. 00:10:58.440 |
And so what happens is the distal terminals of the neurons, illustrated here, begin to 00:11:05.760 |
die back from their synaptic connections in the center of the brain. 00:11:11.300 |
And as a result, you have less and less dopaminergic transmission, and eventually the brain levels 00:11:20.080 |
And when that happens, the classic symptoms of Parkinson's begin. 00:11:24.160 |
And for those of you that aren't familiar with it, the basic symptoms of Parkinson's 00:11:28.160 |
are resting tremor, rigidity of your arms and legs, and then the third one is slowing 00:11:37.160 |
And so Parkinson's patients begin to get slow and stiff. 00:11:41.400 |
And then ultimately, as the disease evolves, they also develop a balance impairment that 00:11:52.000 |
Now there have been a number of drugs that we have evaluated with the goal being to slow 00:11:58.820 |
down the progression of this inexorable disease. 00:12:02.040 |
And many of these I was personally involved with testing. 00:12:07.700 |
The first class I'll tell you about just very briefly are called the MAO-B inhibitors. 00:12:15.420 |
And basically, this is a normal enzyme that every brain has that breaks down dopamine 00:12:25.140 |
The problem with that breakdown is one of those end products is potentially toxic to 00:12:32.300 |
And so we thought, well, if we give a drug that inhibits that, we'll decrease the risk 00:12:42.760 |
Dopamine agonists is another example of drugs that stimulate the dopamine system. 00:12:48.380 |
In animal models, they showed that they could slow the disease progression. 00:12:53.600 |
Bioenergetics, I'm sure you've heard of coenzyme Q10, creatine. 00:12:57.720 |
There was a lot of interest early on that if we give these drugs, they'll help support 00:13:02.600 |
the brain and decrease the rate of cell loss. 00:13:10.040 |
We know that when the brain works, it releases neurochemicals, that if they overdo that, 00:13:18.760 |
So he said if we give something that antagonizes that, maybe that'll help slow the progression. 00:13:27.640 |
Apoptosis is a process where the cells, in effect, commit suicide when their energy levels 00:13:36.720 |
And we know that energy loss is a key component of Parkinson's. 00:13:40.880 |
So we figured if we can inhibit that apoptotic process, that'll help and slow down the progression. 00:13:48.080 |
We also know that inflammation is a huge problem in the brains of Parkinson's patients. 00:13:53.440 |
They develop an increase in the microglia, which are inflammatory cells that cause damage 00:14:01.800 |
Antioxidants, vitamin E, a drug called Inazine. 00:14:07.280 |
We thought that if we could antagonize oxidation in the brain, that surely would slow down 00:14:17.200 |
These are drugs that mimic naturally occurring proteins in the brain that enhance and nurture 00:14:26.440 |
And so we said surely that would slow it down. 00:14:29.320 |
And we even found from a very interesting epidemiologic study that patients who are 00:14:35.360 |
taking a particular drug for blood pressure control had a much lower risk of later developing 00:14:43.040 |
So we said, well, maybe that drug would help to slow down the rate of progression. 00:14:48.560 |
And the results of this were that everything we tried failed, without exception. 00:14:55.660 |
And I can tell you that even as I stand before you today, over 200 years after our formal 00:15:02.100 |
recognition of Parkinson's, we have nothing that slows down the progression of Parkinson's. 00:15:08.080 |
I want to hasten to add, we've got excellent treatments for the symptoms. 00:15:12.840 |
So this remains a highly therapeutic field for us, but we can't do anything about the 00:15:19.140 |
progression of the disease, at least as we stand today. 00:15:24.320 |
So how does this discovery, if you will, of my abject failure of 30 years of research 00:15:39.040 |
First of all, these failures show us the sheer complexity of these neurologic diseases. 00:15:50.120 |
And anybody who tells you we've got the brain figured out is either misguided or lying. 00:15:58.080 |
It also highlights for me the difference in intelligence between the creator and the creature. 00:16:05.360 |
The God that we worship is so much greater than we are, that he has created things that 00:16:13.960 |
So it really is a testimony to the greatness of our creator. 00:16:18.520 |
And therefore, the failure to solve human disease, ironically, strengthens my faith 00:16:26.040 |
This is why we need our faith, because it's real, because there really is a creator. 00:16:32.560 |
And he is so magnificent that he can do these things that we can't even fathom and can't 00:16:40.480 |
And unlike us, Christ is a true healer of disease. 00:16:45.520 |
We doctors do the best we can to palliate suffering, to help people feel better, to 00:16:51.640 |
do whatever is possible to alleviate their suffering. 00:16:55.480 |
But at the end of the day, only our Lord is a healer. 00:17:04.400 |
"Now when evening came, they brought to him many who were demon-possessed. 00:17:09.280 |
And he cast out the spirits with a word, and he healed all who were ill in order to fulfill 00:17:14.800 |
what was spoken through Isaiah the prophet, saying, 'He himself took our infirmities and 00:17:23.240 |
You know, there's a lot in that verse that we can unpack. 00:17:25.880 |
But what I want to point you to today is one little word after the word healed. 00:17:36.920 |
I don't know if you've ever thought about that. 00:17:39.880 |
When our Lord went from town to town in Israel, He was eradicating disease. 00:17:48.340 |
Everybody who was brought to Him was being healed, not just those who had faith in Him. 00:17:53.800 |
In fact, it is infrequent that Christ healed people on the basis of faith. 00:18:00.240 |
Most of the time, He simply eradicated disease wherever He went. 00:18:07.640 |
So what is my goal then in the talk this morning? 00:18:11.640 |
First of all, from neurology, I hope to impress you with just how great a creator God is. 00:18:19.320 |
Secondly, from selected miracles of Christ, I want to show you how powerful our Lord is. 00:18:27.840 |
I want to demonstrate the impossibility that Christ's miracles have a natural explanation. 00:18:35.200 |
And I want to finally prove the point that His healings were actually acts of creation. 00:18:42.440 |
That's what our Lord was doing when He healed disease, is He was recreating whatever was 00:18:51.320 |
So the big idea then for the talk this morning is that Christ's healings were acts of creation. 00:19:01.760 |
And we know this from Colossians 1 verse 16, "For in Him all things were created, both 00:19:09.880 |
in the heavens and on earth, visible and invisible, whether thrones or dominions or rulers or 00:19:16.840 |
authorities, all things have been created through Him and for Him." 00:19:23.120 |
So our Lord is the creator and His acts of healing on this planet during His first coming 00:19:33.600 |
So the miracles I want to review with you this morning in the few moments we have are 00:19:37.840 |
number one, I want to talk to you about the man blind from birth, this famous account 00:19:46.520 |
I want to tell you about the man with the withered hand whom our Lord healed as described 00:19:55.280 |
And I want to tell you briefly about the woman who was crippled for 18 years described in 00:20:04.280 |
So let's begin with the account of blindness from birth. 00:20:08.200 |
I hope you have your Bibles with you today because I want to read this text for you. 00:20:21.200 |
As He passed by, He saw a man blind from birth and His disciples asked Him saying, "Rabbi, 00:20:28.560 |
who sinned, this man or his parents that he would be born blind?" 00:20:33.760 |
Jesus answered, "Neither this man nor his parents sinned, but this was so that the works 00:20:42.820 |
We must work the works of Him who sent Me as long as it is day. 00:20:52.140 |
While I am in the world, I am the light of the world." 00:20:57.460 |
Now when He had said this, He spat on the ground, made clay of the saliva and rubbed 00:21:01.820 |
the clay on His eyes and said to him, "Go wash in the pool of Siloam," which is translated 00:21:08.340 |
So He went away and washed and came back seeing. 00:21:12.380 |
Therefore the neighbors and those who previously saw Him as a beggar were saying, "Is not this 00:21:20.860 |
Still others were saying, "No, but He is like Him." 00:21:27.980 |
So they were saying to them, "How then were your eyes opened?" 00:21:31.380 |
He answered, "The man who is called Jesus made clay and rubbed my eyes and said to me, 00:21:40.220 |
So when I went away and washed, I received sight." 00:21:46.860 |
Now let's talk for a minute about congenital blindness. 00:21:50.180 |
I think you need to understand the significance of this problem. 00:21:56.220 |
Here on the right-hand side you see an illustration of the design of the human visual pathways. 00:22:03.240 |
And it's really brilliant the way this was designed. 00:22:06.140 |
You have here obviously the eyes and light comes in at this angle and hits what you see 00:22:17.220 |
Light coming in from the right-hand side hits the red part of the retina. 00:22:22.500 |
And fascinatingly, these pathways have both an ipsilateral projection and a contralateral 00:22:31.140 |
So you see both eyes that are perceiving the right hand of the world wind up on the right 00:22:37.980 |
side of the brain and the portion of the eyes that sees the left side of the world winds 00:22:45.900 |
So this is the way the human visual system is designed by Christ. 00:22:50.660 |
This little area here is called the lateral geniculate nucleus where the primary first 00:22:56.220 |
order neurons that exist in the retina synapse with the second order neuron that projects 00:23:05.640 |
And it's the brain's occipital lobe that actually perceives what you're seeing. 00:23:16.180 |
You have at birth all of these neurons preformed during the process of genesis in the womb 00:23:27.580 |
But the problem is that if this retina does not see light in the first few days, weeks 00:23:36.360 |
and months of life and not only not seeing light, it has to see formed images. 00:23:45.020 |
What happens is the synapses that occur in the lateral geniculate nucleus don't see the 00:23:51.460 |
release of neurotransmitter because you're not perceiving anything. 00:23:56.340 |
And the result of that is these pathways disintegrate. 00:24:04.180 |
Vision in the first year of life is critical to the actual development of the visual system. 00:24:11.580 |
And so if you are blind from birth, all of these cells that normally go to the brain 00:24:17.380 |
and enable you to perceive light, they die out. 00:24:22.900 |
And this part of the brain literally shrinks. 00:24:25.780 |
A good example of this is congenital cataracts, not a terribly uncommon condition. 00:24:31.700 |
This has to be detected immediately after birth so those cataracts can be removed to 00:24:37.780 |
enable the infant to see so this visual system will develop. 00:24:42.820 |
So in our example here from John, the patient never developed any of these networks. 00:24:50.700 |
And therefore, nothing you do to fix the eye or even the retina will solve the problem 00:24:57.020 |
because the neural pathway that perceives vision has failed to develop. 00:25:02.780 |
And so it can't be corrected by any means that's available to us. 00:25:07.180 |
The only fix for congenital blindness is a complete recreation of the entire network 00:25:17.020 |
And as we saw in our text, Christ did this effortlessly because he is the creator. 00:25:34.140 |
And his disciples asked him, saying, "Rabbi, who sinned, this man or his parents, that 00:25:40.660 |
Jesus answered, "Neither this man nor his parents sinned, but this was so that the works 00:25:49.340 |
We must work the works of him who sent me as long as it is day. 00:25:55.820 |
While I am in the world, I am the light of the world." 00:25:59.780 |
Now this verse is fascinating to me because you notice what the disciples' initial reaction 00:26:09.140 |
We call this the divine retribution principle. 00:26:12.660 |
This is very similar to what we see taught in the book of Job. 00:26:16.760 |
And I had the privilege of teaching through the book of Job in our Sunday school class 00:26:20.900 |
at Countryside for several years and was just amazed at how pervasive this view was. 00:26:37.060 |
This is not the divine retribution principle. 00:26:40.240 |
This was allowed to happen just so I could do this miracle." 00:26:45.300 |
Think about the sovereignty of Christ in making this situation occur so that he could demonstrate 00:26:55.740 |
And of course, the act of creating sight where once there was only darkness serves to picture 00:27:01.640 |
in the physical world the truth that Jesus is the light of the world spiritually. 00:27:10.280 |
This is a test question I'm going to ask you here since we're in a university. 00:27:17.000 |
John 8, John 9, 8-9, "Therefore the neighbors and those who previously saw him as a beggar 00:27:21.780 |
were saying, 'Is not this the one who used to sit and beg?' 00:27:27.280 |
Still others were saying, 'No, but he is like him.' 00:27:34.600 |
"Then the Jews did not believe it of him that he was blind and had received sight until 00:27:39.600 |
they called the parents of the very one who had received sight and questioned them, saying, 00:27:44.320 |
'Is this your son who you say was born blind?' 00:28:05.720 |
Because no one has ever heard of anyone receiving sight when they were born blind. 00:28:23.160 |
But even they knew that if you were born blind, it was impossible to receive sight. 00:28:42.360 |
"Therefore, a second time they called the man who had been born blind and said to him, 00:28:51.880 |
Then he answered, 'Whether he is a sinner I do not know. 00:28:55.200 |
One thing I do know, that though I was blind, now I see.' 00:29:04.360 |
He answered them, 'I told you already, and you did not listen. 00:29:14.440 |
"And they reviled him and said, 'You are his disciple, but we are disciples of Moses. 00:29:21.680 |
We know that God has spoken to Moses, but as for this man, we do not know where he is 00:29:27.920 |
The man answered and said to them, 'Well, here is a marvelous thing, that you do not 00:29:32.320 |
know where he is from, and he opened my eyes. 00:29:35.800 |
We know that God does not listen to sinners, but if anyone is God-fearing and does his 00:29:43.520 |
Since the beginning of time, it has never been heard that anyone opened the eyes of 00:29:50.120 |
If this man were not from God, he could do nothing.'" 00:29:53.800 |
What a testimony of his experience and his faith. 00:29:59.520 |
"They answered and said to him, 'You were born entirely in sins, and are you teaching 00:30:14.560 |
What infuriated the Jewish leaders even more than healing on the Sabbath, which was a major 00:30:20.200 |
bone of contention they had with our Lord, was the incontributable proof in what happened 00:30:27.120 |
to this man that Jesus was the Christ, the Son of God. 00:30:32.200 |
He recreated this man's entire visual system, and no one can do that but God alone. 00:30:45.080 |
They did not want to receive him, and so a miracle like this put them in a huge bind 00:30:51.600 |
because no one could dispute that a supernatural act had occurred. 00:30:58.440 |
Let me move on to our next one, the miracle of the withered hand. 00:31:08.680 |
Let's read Matthew 12, 9-14, "And departing from there, he went into their synagogue. 00:31:19.280 |
And behold, a man was there whose hand was withered. 00:31:23.080 |
And they questioned Jesus, saying, 'Is it lawful to heal on the Sabbath, so that they 00:31:29.920 |
And he said to them, 'What man is there among you who has a sheep, and if it falls into 00:31:34.480 |
a pit on the Sabbath, will not take hold of it and lift it out? 00:31:39.520 |
How much more valuable, then, is a man than a sheep? 00:31:43.480 |
So then it is lawful to do good on the Sabbath.'" 00:31:48.160 |
Verse 13, "Then he said to the man, 'Stretch out your hand.' 00:31:53.480 |
He stretched it out, and it was restored to normal like the other." 00:31:58.440 |
Again, it appears almost effortless what Christ is doing and how He is executing these healings. 00:32:06.760 |
Now from a medical perspective, we can't know for certain what disease this man had. 00:32:12.320 |
As I've thought about it, I think there are three major possibilities. 00:32:16.200 |
The first one would be a traumatic fracture with poor healing. 00:32:20.400 |
We know that if you fracture the hand badly enough and it doesn't heal correctly, it can 00:32:28.560 |
It could also represent severe arthritis with joint deformity. 00:32:35.220 |
But the third possibility, and the one I am choosing to impose on the text, is that this 00:32:44.360 |
Hand dystonia, a very interesting problem that fell within the realm of my treatment. 00:32:50.160 |
I'm going to show you a videotape of a patient I had who had this disease, just to illustrate 00:33:00.300 |
So you can clearly see that, in her case, it's bilateral. 00:33:04.400 |
But notice that her hand is clearly withered. 00:33:11.920 |
And because the dystonia has been long-lasting, it's produced permanent deformity in the position 00:33:19.540 |
So her hands are essentially non-usable because of the persistence of this dystonia. 00:33:34.180 |
This is a fascinating neurologic disease, which, to be honest with you, we don't understand 00:33:44.080 |
Unlike Parkinson's disease, where I can show you where in the brain the problem is, I can't 00:33:50.920 |
We know it is something to do with brain neural networks. 00:33:56.740 |
And neural networks are just what they sound like. 00:33:59.080 |
They're similar to an electrical network that you would have for the electrical grid. 00:34:07.140 |
It's a situation where neurons are synapsing with other neurons in a very complex pattern 00:34:13.720 |
that results in the ability to execute a movement. 00:34:18.520 |
Now in the case of dystonia, there is no known cure for this. 00:34:21.720 |
So in that respect, it's similar to Parkinson's disease. 00:34:25.240 |
And unfortunately, unlike Parkinson's disease, we don't have good drugs for dystonia. 00:34:31.400 |
What I would typically tell my patients who came to me with dystonia when we're talking 00:34:35.400 |
about oral drugs is that I've got about a 50% chance of giving you a 20% improvement. 00:34:46.240 |
There were a handful of drugs that we would employ. 00:34:48.800 |
Every now and then we saw a patient who did well, but basically it was difficult to treat. 00:34:54.300 |
Now there is a newer treatment called botulinum toxin. 00:34:58.080 |
You may have heard of Botox that has revolutionized our treatment for dystonia. 00:35:04.520 |
The way it works is you inject this directly into whatever muscle is contracting abnormally. 00:35:12.000 |
And because botulinum toxin is a paralytic agent, it weakens that muscle. 00:35:16.920 |
And so you can have less of whatever the abnormal pulling is. 00:35:20.920 |
But there are two major problems with this treatment. 00:35:23.740 |
The first one is there's a limit to how much of it I can give you. 00:35:27.600 |
You've all heard of botulism, which is a fatal disease if you get too much toxin in your 00:35:33.360 |
So we're limited to how big the muscle is that we can inject this with to achieve benefit. 00:35:40.060 |
And the second problem is the muscular activity that produces dystonia is so complex that 00:35:47.680 |
we really can't figure out exactly how to balance this out to achieve perfect results. 00:35:54.080 |
And that's why I say it works for a short time, but it never produces normalization 00:36:00.160 |
It makes them better, but by no means perfect. 00:36:04.800 |
Every three to four months you have to repeat that injection ad infinitum as long as the 00:36:11.720 |
What can I tell you about this human neural network that's involved in dystonia? 00:36:17.560 |
The human brain has 86 billion neurons, just for you to contemplate that. 00:36:24.760 |
That correlates to 100 trillion connections among neurons. 00:36:30.520 |
I hope you're beginning to sense the complexity of this system. 00:36:34.800 |
It is staggering how complex the human neural network is. 00:36:40.400 |
And the best science of man has no real idea how the brain works, much less how to fix 00:36:49.440 |
We know it's there, we dabble in drugs, but at the end of the day, if the network is bad, 00:36:57.240 |
Well, what was Christ's solution to the withered hand? 00:37:06.520 |
He stretched it out and it was restored to normal like the other. 00:37:11.720 |
I have never had a patient with dystonia that I made normal, not one in 30 years. 00:37:19.680 |
Christ did it effortlessly in a moment in time. 00:37:24.320 |
How do you get a malfunctioning neural network normal? 00:37:29.760 |
Only one way I know of, you recreate it ex nihilo. 00:37:36.560 |
Everyone witnessing this knew immediately that this was a miracle. 00:37:41.080 |
In this simple command, our Lord is recreating his neural network. 00:37:46.560 |
And keep in mind that what he corrected was of a staggering level of complexity, a hundred 00:37:58.600 |
Now in seeing this act of creation, our observers had only one of two options. 00:38:05.440 |
They could either bow the knee to the King of Kings, they could recognize that this was 00:38:10.440 |
the Messiah who had been prophesied and who they were all waiting for, or they had to 00:38:17.480 |
attribute the power demonstrated to Satan and purpose to kill him. 00:38:25.160 |
So what was the reaction then of the Pharisees? 00:38:28.680 |
Well we see that clearly in verse 14, "But going out, the Pharisees took counsel together 00:38:34.140 |
against him as to how they might destroy him." 00:38:40.520 |
Now I've thought a lot about this over the years as I've studied the Scripture and learned 00:38:46.320 |
about our Lord and the events, and it's very difficult to understand why they did this. 00:39:01.400 |
We have the predictions all throughout the Scripture, including in Moses, that a future 00:39:07.960 |
Messiah is coming who's gonna right all the wrongs and redeem the nation. 00:39:14.400 |
Everybody is looking forward to this Messiah, and all of a sudden, in a point of time, he 00:39:26.480 |
He fulfills every Scripture that was prophesied about him, and he demonstrates the power that 00:39:34.600 |
And yet, the people that he came to rejected him, and the Pharisees led that. 00:39:40.680 |
They were the ones that were determined from the beginning to kill him. 00:39:46.600 |
I think there are two Scriptures that help us to answer that. 00:39:49.760 |
The first was a parable that our Lord told in Luke 19, where he's describing the situation 00:39:59.280 |
So he said, "A nobleman went to a distant country to receive a kingdom for himself and 00:40:05.520 |
And he called ten of his slaves, gave them ten minas, and said to them, 'Engage in business 00:40:12.840 |
But his citizens hated him and sent a delegation after him, saying, 'We do not want this man 00:40:22.640 |
What our Lord is doing there is he's telling a parable that is describing the condition 00:40:36.200 |
It's because they no longer were true Israelites. 00:40:40.660 |
They had now a false religion, not a true religion. 00:40:45.080 |
Their false religion was one based on self-righteousness, based on works. 00:40:50.600 |
And so when their true Messiah came, they rejected him because they did not want to 00:40:59.960 |
Now that's a parable, and you might say, "Well, how do I know that's really what happened?" 00:41:03.640 |
Well, here's the definitive answer in John 11, verse 47 and following, "Therefore the 00:41:10.360 |
chief priests and the Pharisees gathered the Sanhedrin together and were saying, 'What 00:41:19.320 |
If we let him go on like this, all will believe in him, and the Romans will come and take 00:41:47.440 |
They would not bow the knee to their Messiah. 00:41:51.720 |
Well, let's move to our third illustration, "The Woman Crippled for Eighteen Years." 00:42:02.140 |
Let's turn to Luke 13, chapter 10, verse 10 and following, "And he was teaching in one 00:42:14.700 |
And behold, there was a woman who for eighteen years had a sickness caused by a spirit, and 00:42:20.400 |
she was bent double and could not straighten up at all. 00:42:25.800 |
But when Jesus saw her, he called her over and said to her, 'Woman, you are freed from 00:42:34.780 |
And he laid his hands on her, and immediately she was made erect again and began glorifying 00:42:47.480 |
Now does that sound like a transient passing illness that one can recover from readily? 00:42:57.280 |
Now I find it interesting, the text indicates that her malady was due to an evil spirit, 00:43:06.000 |
But in my view, it is more likely that a demon had caused her physical affliction rather 00:43:12.080 |
than that this was a case of demon possession. 00:43:16.360 |
It's because normally when Christ confronted a demon-possessed person, his action was to 00:43:23.240 |
Here we have a sickness that was demonically induced, but it's a physical malady. 00:43:35.320 |
And of course in this text, he simply heals her by laying his hands upon her. 00:43:47.200 |
So I guess I could call this my second test question. 00:43:51.000 |
Anybody know what disease causes you to be bent over double for eighteen years? 00:43:57.960 |
Well first of all, I've got to show you what it looks like. 00:44:03.920 |
So that's the position she's in for eighteen years. 00:44:09.280 |
Anybody in the audience ever heard of a disease that causes that? 00:44:14.560 |
Well believe it or not, there actually is one. 00:44:17.560 |
Only a neurologist would know about this, and particularly a movement disorders neurologist. 00:44:24.680 |
This is a disease called Camptichormia, also known as bent spine syndrome. 00:44:38.940 |
And because I want you to see this, we'll give you a videotape illustration of it. 00:44:51.280 |
Well first of all, if you look at the literature, there is a report of a very interesting scenario 00:45:01.940 |
And in effect, what they did is they developed that bent spine posture. 00:45:06.520 |
Now as you may recall, in World War I, there was a lot of trench warfare. 00:45:11.280 |
And so the way that you didn't get your head blown off is when you're in the trenches, 00:45:17.960 |
Well what was weird is these people continued to do that even when they were not in the 00:45:23.960 |
So looking back on that historically, this is most likely a case of malingering, where 00:45:29.080 |
basically they figured out that if I couldn't straighten my spine, I would get sent back 00:45:34.480 |
to the hospital away from the front lines and get out of it. 00:45:38.840 |
So that's where we first see in the literature descriptions of Camptichormia. 00:45:43.880 |
However, there are some organic, bona fide neurological diseases that cause this. 00:45:50.440 |
One of them is called primary axial myopathy. 00:45:53.800 |
So if you think about it, the only way you can remain erect is because you have this 00:46:02.640 |
They're called the erector speedi muscles, and they're the ones that enable you to arch 00:46:09.040 |
And when you're standing up straight, they hold your spine up. 00:46:12.080 |
If those muscles go away, you're going to crumple forward with the action of gravity 00:46:18.880 |
And you can develop an atrophy of those muscles. 00:46:23.660 |
Those neurons or those muscles that control the spine's erection can disappear, an atrophy. 00:46:32.280 |
Totally unknown why this occurs, but it's a bona fide condition. 00:46:37.140 |
And then the third one, of course, the case where I come in, is with axial dystonia. 00:46:44.180 |
So this is similar to the patient I showed you with the hand dystonia, but believe it 00:46:48.820 |
or not, you can also get this affecting the spine. 00:46:52.340 |
And in this particular illustration, what we think happens is there are muscles on the 00:46:58.780 |
front side of your body, in the abdomen, that are deep. 00:47:02.700 |
They're not the superficial muscle that you can palpate. 00:47:06.860 |
They're deep muscles that run along the surface of the spine anteriorly that begin to contract 00:47:15.280 |
And just as the lady I showed you affects her fingers due to abnormal muscle contraction, 00:47:20.580 |
here we have abnormal muscle contraction of the anterior muscles of the spine that is 00:47:29.260 |
And again, dystonia is a neural network problem. 00:47:36.220 |
This is a man, obviously, but this is the patient that our Lord healed. 00:47:44.860 |
He is unable to erect his spine any higher than this when walking. 00:47:51.340 |
And this is one of the clues that we have that this is dystonia, is because when sitting 00:47:59.780 |
In fact, he can even arch his spine when sitting down. 00:48:03.420 |
But when he stands up and begins to walk immediately and progressively, he begins to flex more and 00:48:11.300 |
So what's happening basically is due to an abnormality in the brain's neural network 00:48:17.280 |
that controls gait, when he starts to pull up that motor program of walking, it progressively 00:48:26.780 |
causes the aberrant contraction of those muscles that we don't want to contract when we're 00:48:32.780 |
walking, ultimately causing him to flex forward like that. 00:48:43.220 |
Well, if it's a psychological problem, again, there are reports that this could be treated, 00:48:52.180 |
Again, the main problem with those World War I soldiers is they were getting out of a dangerous 00:49:00.020 |
So that's not applicable to most people today. 00:49:07.300 |
Once those muscles begin to degenerate in the spine, there's really nothing you can 00:49:18.380 |
Now axial dystonia in Parkinson's disease, which is my patient, there have been individual 00:49:24.160 |
case reports of the drug for Parkinson's called levodopa helping. 00:49:30.360 |
There have also been reports of deep brain stimulation. 00:49:33.540 |
So it's a new technology now for treatment of Parkinson's where you implant wire electrodes 00:49:38.480 |
into the center of the brain and basically hook them up to a spinal stimulator that stimulates 00:49:47.060 |
There have been isolated reports of patients improving with that. 00:49:51.460 |
But none of those are longstanding permanent cures. 00:49:55.720 |
They may produce temporary improvement in the bent spine, but they don't solve it. 00:50:00.660 |
I also tried in a couple of my patients with this botulinum toxin thinking, "Well, maybe 00:50:05.320 |
if I can find the muscle that's pulling the patient down, we can weaken that muscle and 00:50:11.920 |
Again, the problem is the muscles were too deep. 00:50:14.800 |
I couldn't get to them through the exterior and sufficiently weaken the muscles that were 00:50:23.600 |
And that's the fundamental problem we have with campnicormia. 00:50:27.840 |
We cannot regenerate atrophic muscle cells, nor can we correct the complex neural network 00:50:38.560 |
In spite of the advanced state of medical knowledge in the 21st century, we're helpless 00:50:48.620 |
Well, when Jesus saw her, he called her over and said to her, "Woman, you are freed from 00:50:55.000 |
And he laid his hands on her, and immediately she was made erect again and began glorifying 00:51:03.240 |
Notice that Christ spoke to and touched this woman, and immediately she was healed. 00:51:08.640 |
We know from other miracles of Christ that he didn't need to do either of those two things. 00:51:13.320 |
He had the power to recreate her neural network without uttering a word or a touch. 00:51:23.180 |
He wanted the physical touch of her to reemphasize his love for her. 00:51:29.780 |
Instantly her thoracic muscles were restored, her neural network was recreated, and our 00:51:36.420 |
Lord healed this woman because he is compassionate and merciful. 00:51:43.100 |
His act of recreation shown here was effortless and once again proving that he was God the 00:51:49.940 |
creator and proving that there could not be a natural explanation for this because you 00:52:05.220 |
Why did I pick these three particular miracles to show you today? 00:52:10.060 |
Well first of all, all three addressed unsolvable neurologic problems that have no possibility 00:52:24.300 |
And in all three cases we see an act of creation, a brand new restoration of normal function 00:52:35.560 |
So taken together, these miracles establish beyond any doubt that Jesus had divine supernatural 00:52:46.200 |
That God, not Satan, was the source of the power is proven by the beneficial result of 00:52:53.800 |
He restored to health whereas demonic action always degrades the person and causes illness. 00:53:01.600 |
And this is why the Pharisees claim that, "Oh well, Christ is doing this by the power 00:53:10.080 |
Nobody bought that because demonic forces don't heal people. 00:53:18.060 |
But that was the only thing they could think of to try to explain away the miraculous work 00:53:25.800 |
I think it's also noteworthy that all three miracles took place on the Sabbath, thus 00:53:31.800 |
serving to condemn the Pharisees' hypocritical approach to a day God intended to be beneficial 00:53:44.880 |
What's the take-home message that I think each of us can take from this? 00:53:50.520 |
Well first, I think consideration of these miracles should humble us. 00:53:55.160 |
You've probably heard that there are some doctors somewhere who develop a God complex. 00:54:05.960 |
It's really amazing to be in a position where a patient will come to you suffering with 00:54:11.360 |
sickness and say, "Doctor, whatever you tell me to do, I'll do it because I want to get 00:54:18.080 |
That is an immense trust that they're placing in us. 00:54:22.000 |
And more often than not, they adhere to what we recommend. 00:54:26.500 |
And if you're an unbeliever and you're prone to pride, which all of us are, that can very 00:54:32.500 |
rapidly lead to pride and escalation of your own view of yourself. 00:54:38.720 |
But when we think about Christ's miracles and how much more powerful He is, that once 00:54:45.040 |
again humbles us and shows us that no, we really can't do anything. 00:54:50.040 |
Our efforts are pathetic and ineffectual compared to how our Lord dealt with this. 00:54:57.560 |
Second, I think these miracles should strengthen our faith in Christ. 00:55:03.360 |
If Jesus could recreate neural networks effortlessly in His first coming, He can also forgive sins, 00:55:12.280 |
which God alone can do, and that's our real problem, isn't it? 00:55:17.880 |
Our separation from Him spiritually is our real problem. 00:55:21.940 |
And if He can do this, He has proven that He is God and God can forgive sins. 00:55:29.280 |
And then, of course, His healing of physical dysfunction by His divine power at His first 00:55:34.720 |
coming is illustrative of His power to overcome spiritual death now and to raise us physically 00:55:45.580 |
We worship a God who is truly powerful, and therefore, we can trust Him that He will rescue 00:55:53.240 |
us and He will raise us with Him on the last day. 00:55:58.400 |
And then finally, these miracles should embolden us to share the gospel with others. 00:56:04.060 |
As believers, we need to be growing in compassion toward the lost. 00:56:08.240 |
This is what Christ's example to us was of a compassionate, loving Savior. 00:56:16.740 |
All of His healings were motivated by compassion for suffering people, and as I said earlier, 00:56:21.460 |
most of them were totally disconnected from any faith that person had. 00:56:27.820 |
He wanted to do this because it was a reflection of Himself, His character. 00:56:34.180 |
And we need to do that ourselves, and we need to have a compassion for the lost, and therefore, 00:56:40.580 |
if we care about the lost, we'll share the gospel whenever we can. 00:56:58.340 |
Thank you so much, Dr. Dewey, that was phenomenal. 00:57:03.220 |
I know you just sat down, but does anyone have any questions? 00:57:06.500 |
We have some folks joining by live stream, so if you have a question, just raise your 00:57:19.820 |
Okay, so we have a microphone coming up front. 00:57:31.820 |
My question is with regard to the second example that you gave, the man with the withered hand, 00:57:37.180 |
how it specifically talks about it being only one hand that was affected. 00:57:47.540 |
The example I showed, obviously, was bilateral. 00:57:50.460 |
In fact, that patient had generalized dystonia. 00:57:53.860 |
So her whole body was affected, but she was the best video I had showing the hand involvement. 00:57:59.500 |
But actually, more often than not, when we see focal dystonia, it affects one hand or 00:58:09.440 |
I was just wondering, or actually noticing that not only was the full recreation of the 00:58:22.940 |
brain and all the neurons connected, but the training and understanding of how to use them 00:58:29.380 |
-- we just can't take a paralytic who's never walked and make them have perfect balance 00:58:35.780 |
It takes years of rehab, even if everything was working. 00:58:42.940 |
You put knowledge into these people's brain, muscle memory into these people. 00:59:02.100 |
My father was a neurologist, by the way, so I have a little bit of knowledge, small amount. 00:59:09.780 |
Other diseases that are motor-related, like ALS, things like that, maybe just a few words 00:59:21.980 |
Well, most of the diseases that you think of in neurology that are bad, like ALS, they're 00:59:29.500 |
So what's happening is there is something that's going wrong in the metabolism of the 00:59:38.780 |
There are fortunately a few neurologic diseases that aren't that way. 00:59:46.020 |
And there are a few others that I would consider to be not as serious that don't involve degeneration. 00:59:52.020 |
What's fascinating is that the two most common in the elderly population are Parkinson's 00:59:58.620 |
And we now know, interestingly, that both of them are due to these depositions of small 01:00:09.320 |
And what's fascinating is the proteins that clump are normal brain proteins. 01:00:14.780 |
All of our brains are chock full of those proteins. 01:00:18.460 |
They have specific functions that carry out things that we need to be able to do. 01:00:23.540 |
But it's when they start to behave in an abnormal way and they start to precipitate into small 01:00:29.580 |
clumps that they cause the pathology and ultimately cause cell death. 01:00:35.340 |
And unfortunately, we don't have any treatments that stop the degenerative diseases of the 01:00:45.300 |
I'm not going to be greedy, just pick one of them. 01:00:51.180 |
First in John 9, my favorite, it's like the sweetest man on earth. 01:00:56.620 |
I believe he heard the disciples and Jesus talking and he realized at some point, yes, 01:01:02.660 |
I was born blind for this purpose, which is just stunning. 01:01:06.580 |
But the second one is a lady doctor from Argentina who, of course, can't practice here, but she 01:01:11.300 |
told me her patients, she knew they had spiritual problems and she couldn't help with that. 01:01:17.140 |
All she could do was tend to their body, which was disturbing if you want to talk about that. 01:01:21.540 |
The third is what the chemo gave me induced Parkinson's like shakes, which is that a route 01:01:27.980 |
to demystify those kinds of things and it'd be horrible to do to somebody, but we had 01:01:46.140 |
We don't understand it very well, but the one thing we do know is that all chemotherapeutic 01:01:52.100 |
agents work by destroying cells in your body. 01:01:56.000 |
So it is not beyond speculation that in particular individuals, the chemotherapy may be mis-targeting 01:02:05.660 |
the cells that are involved in the Parkinson pathway, producing that side effect. 01:02:11.340 |
But I would have to say that's considered exceptionally unfrequent. 01:02:16.640 |
So we don't normally see patients with Parkinsonism who have chemotherapy-induced disease. 01:02:22.100 |
I wouldn't rule it out as it being a possible on an individual basis, but it's not the rule 01:02:28.740 |
And I think your other question about how do you deal with the spiritual problems of 01:02:32.820 |
your patients if you're a doctor, that's a big one. 01:02:35.900 |
I'm going to defer that to the discussion tomorrow.