How to Increase Growth Hormone | Dr. Kyle Gillett #shorts
00:00:00.000 | What is the relationship between fasting and growth hormone release?
00:00:02.920 | I find this really interesting.
00:00:04.280 | Fasting certainly potently increases growth hormone release.
00:00:08.320 | However, the end-binding to the receptor is less sensitive.
00:00:14.760 | So although fasting does increase growth hormone,
00:00:18.040 | the genes that are downstream to it,
00:00:21.240 | both the growth hormone genes and IGF-1-related gene transcription activity
00:00:26.760 | will not be significantly higher.
00:00:30.040 | However, if you are optimizing the growth hormone
00:00:34.040 | that is released as pulsatile secretion,
00:00:37.800 | it is helpful to avoid eating for two hours.
00:00:40.360 | So the general rule of thumb is avoid eating about two hours before bed.
00:00:43.440 | I think that's clinically significant and helpful,
00:00:46.040 | but fasting otherwise specifically for growth hormone optimization
00:00:49.960 | in someone who already has normal growth hormone signaling is not helpful.