Are You Prone to Alcoholism? #shorts
00:00:00.000 | So actually people who have so little alcohol dehydrogenase
00:00:02.580 | that when they ingest alcohol,
00:00:04.020 | they get very red and they just feel sick.
00:00:05.780 | So if you're somebody that has a sip of alcohol
00:00:07.260 | and you just feel horrible, it makes you feel nauseous,
00:00:09.500 | chances are you have gene variants
00:00:11.900 | that create a situation where you're not making
00:00:13.900 | very much alcohol dehydrogenase,
00:00:15.700 | you just simply can't metabolize alcohol.
00:00:17.780 | So you just get a rapid buildup
00:00:19.300 | of the toxic effects of alcohol, the acetyl aldehyde.
00:00:22.340 | You're not converting it into those empty calories.
00:00:24.540 | In cultures where you have a lot of genetic variants
00:00:27.340 | and genes expressed in people
00:00:29.180 | where they have a lot of alcohol dehydrogenase,
00:00:31.280 | sure, they can drink more
00:00:32.980 | and they're converting more of that alcohol
00:00:34.620 | from its toxic form to a non-toxic form.
00:00:37.180 | And yes, of course, you will observe more alcoholism
00:00:40.020 | in those communities because they're drinking more.
00:00:42.140 | But I do wanna emphasize that the environmental factors
00:00:45.180 | are playing a strong role there too,
00:00:46.580 | because if you can drink more, you're likely to drink more.
00:00:48.980 | If you're somebody that feels sick immediately
00:00:50.960 | from drinking, it's likely that you're not gonna engage
00:00:52.780 | in alcohol consumption,
00:00:54.300 | especially if these things are genetically related
00:00:56.580 | and of course, genes and culture and location
00:00:58.740 | in the world tend to run together.