back to indexOptimize Your Learning & Creativity With Science-Based Tools | Huberman Lab Essentials
Chapters
0:0 Huberman Lab Essentials; Neuroplasticity
1:50 Types of Neuroplasticity
3:46 Autonomic Arousal, Sleep
5:6 Waking Up, Tools: Sunlight, Caffeine Delay, Hydration
8:11 Alertness, Morning & Work Bout
9:37 Dopamine & Learning; Tool: Music & Alertness
12:56 Tool: Exercise Early; Morning Work
14:14 Meals; Afternoon Dip & Work, Tools: Hydration, Non-Sleep Deep Rest (NSDR)
16:37 Creativity: Exploring vs. Implementation
19:0 Psychedelics, Sensory Blending; Tool: Timing Creative Work
21:6 Tool: Evening Sunlight; Lights, Evening Meal & Carbohydrates
23:8 Natural Sleep/Wake Schedule; Tools: Anticipate Evening Alertness; NSDR
26:25 Work & Daily Schedule, Tool: 90-Minute Work Bouts
27:42 Optimize Biological Rhythms & Tools for Creativity & Learning
00:00:04.380 |
for the most potent and actionable science-based tools 00:00:07.560 |
for mental health, physical health, and performance. 00:00:13.080 |
and I'm a professor of neurobiology and ophthalmology 00:00:21.660 |
let's talk about how we can optimize our brains. 00:00:28.180 |
of our nervous system that allows it to change itself, 00:00:36.680 |
Our liver can't decide to just change itself. 00:00:39.520 |
Our spleen can't decide to just change itself 00:00:46.880 |
The cells in those tissues can make changes, sure, 00:00:56.760 |
in ways that we believe or we're told will serve us better. 00:01:08.780 |
of how does one go about optimizing their brain 00:01:13.900 |
What is this thing that we're calling optimizing the brain? 00:01:24.020 |
have asked for very concrete examples of what I do and when, 00:01:28.580 |
and so I want to open up the discussion today 00:01:31.740 |
by emphasizing something that's fundamentally important, 00:01:38.900 |
The goal is to figure out how to access plasticity 00:01:49.840 |
Let's start by talking about the different systems 00:01:53.180 |
within the nervous system that are available for plasticity. 00:01:57.220 |
And in doing so, I'll frame them in the context 00:02:04.740 |
First of all, there are several forms of plasticity. 00:02:10.080 |
The best way to think about it is in terms of short-term, 00:02:19.900 |
that you want to achieve in the moment or in the day, 00:02:23.980 |
but that you don't necessarily want to hold onto forever. 00:02:26.820 |
And I'd say, well, what kinds of things are those? 00:02:28.780 |
Well, for instance, short-term plasticity might be 00:02:31.860 |
you wake up earlier than you would like to catch a flight, 00:02:40.420 |
or you decide to use a protocol, which could be coffee, 00:02:49.560 |
But your expectation is that when you return home, 00:02:53.100 |
you will discard the need to do that at 5.30 a.m. 00:02:58.500 |
So there's short-term plasticity, behavioral plasticity. 00:03:03.740 |
For instance, if you go on vacation to Costa Rica 00:03:06.740 |
and you don't know your way around Costa Rica, 00:03:08.700 |
you want to learn the different town and the routes there, 00:03:11.100 |
but you don't have any intention of going back, 00:03:14.000 |
You want to just program it in for sake of your time there, 00:03:25.760 |
so that their brain reflexively works differently. 00:03:29.240 |
Long-term plasticity is almost always the big goal. 00:03:33.520 |
It's I want to know how to speak that language. 00:03:38.760 |
I'm going to frame all this in the context of the daily life, 00:03:48.820 |
and optimizing your brain rides on a deeper foundation 00:03:58.440 |
and in fact, governs all our life called autonomic arousal, 00:04:01.840 |
which is that we're asleep for part of the 24-hour cycle 00:04:09.560 |
occurs during high focus, high alertness states, 00:04:16.460 |
because of the neurochemicals associated with those states. 00:04:19.540 |
But the actual rewiring and the reconfiguration 00:04:28.880 |
So you trigger the change and in sleep, you get the change. 00:04:32.180 |
So some of the things that we'll talk about today 00:04:35.220 |
about optimizing the brain are centered around not sleep, 00:04:41.620 |
We have this system of neurons in our brain and body 00:04:44.300 |
that's just incredible that wake us up and make us alert. 00:04:48.860 |
And when we're not accessing that system well, 00:04:51.580 |
we cannot access plasticity, we cannot optimize our brain. 00:04:55.220 |
Likewise, if we cannot sleep well and we can't rest well, 00:04:59.180 |
we will not access plasticity and rewire our brain 00:05:06.860 |
So to set this in context, I wake up each day 00:05:14.300 |
I usually don't feel like bouncing right out of bed. 00:05:17.540 |
I wake up generally more tired and groggy than I would like 00:05:24.680 |
What it means is that I'm not really matching 00:05:28.540 |
my hardwired needs of going to bed probably at 8.30 or 9 00:05:41.060 |
but I have to do something in order to access that. 00:05:47.540 |
oh no, he's going to tell us to get sunlight in our eyes 00:06:01.220 |
these sunlight detecting, bright light detecting cells 00:06:09.860 |
between these melanopsin cells and the circadian clock 00:06:15.260 |
So there's an opportunity for short-term plasticity. 00:06:18.020 |
So that's why I view sunlight first thing in the day, 00:06:21.100 |
The other thing that I do is that there's a circuit 00:06:26.300 |
and our adrenals that I've talked about before 00:06:37.420 |
The other thing that I do is I delay my intake of caffeine 00:06:43.420 |
Earlier, we talked about the adenosine system 00:06:46.220 |
and how the accumulation of adenosine makes us sleepy 00:06:49.540 |
and caffeine suppresses adenosine, it makes us feel alert. 00:06:57.700 |
I'm able to capture and reinforce to potentiate 00:07:01.460 |
the neural circuit that exists between the circadian clock 00:07:06.380 |
as well as leave those adenosine receptors unoccupied 00:07:10.580 |
so that I can then use the caffeine to get a natural lift 00:07:21.260 |
I also make sure I hydrate first thing in the morning. 00:07:41.200 |
but dehydration can compound the vulnerability 00:07:46.700 |
So I drink water, I drink black coffee, or I drink mate, 00:07:49.300 |
which is just because I have Argentine lineage, 00:07:54.980 |
but I delay it until two hours after I wake up. 00:08:01.520 |
between my eye and my circadian clock and my adrenals 00:08:07.220 |
so that then later the caffeine is an addition, 00:08:11.340 |
Now, this is a discussion about how to optimize your brain. 00:08:16.940 |
and just naturally feel like bouncing out of bed, 00:08:21.300 |
they will do just fine by going into a learning bout 00:08:33.380 |
Here's more or less a rule about how the brain functions 00:08:54.020 |
And our autonomic arousal, or our alertness rather, 00:09:04.860 |
that's a great time to move right into things that, 00:09:29.620 |
And I think many people out there will relate, 00:09:42.780 |
is directly related to the hundreds of questions 00:09:46.460 |
Should I use background music in order to learn? 00:09:49.760 |
So as a rule of thumb, if you're feeling too keyed up, 00:09:53.220 |
then silence and quiet is going to be helpful. 00:09:57.820 |
a particular circuit related to the basal ganglia 00:10:08.900 |
to a structure in our brain called the basal ganglia, 00:10:11.340 |
which is actually a collection of structures. 00:10:13.380 |
And the forebrain, which is involved in rational thought 00:10:22.660 |
And the basal ganglia are intimately involved 00:10:30.220 |
The basal ganglia has one set of connections to the cortex 00:10:41.020 |
And the molecule, the neuromodulator dopamine, 00:11:06.740 |
involves dopamine binding to this other receptor 00:11:12.660 |
Now, D1, D2 receptors, you can't just consciously decide, 00:11:19.340 |
You have to think about which sorts of states of mind 00:11:24.260 |
and body facilitate go and which ones facilitate no-go. 00:11:29.260 |
There are three sort of levels of autonomic arousal, 00:11:34.300 |
of alertness that bias us more toward go, no-go, or both. 00:11:43.060 |
Maybe I got a particularly good night's sleep 00:11:44.700 |
the night before, I had a little too much coffee 00:11:50.020 |
The thing to know, and what I always tell myself, 00:11:52.780 |
is when I'm very alert, I am very prone to go to action, 00:12:03.100 |
I'm not going to be very good at suppressing action. 00:12:12.820 |
So those are push-pull, toward action, suppress action. 00:12:26.900 |
When you are very alert, the best situation for learning 00:12:37.180 |
and you're kind of sleepy, a lot of people find 00:12:51.180 |
in which they're most alert throughout the day. 00:13:02.260 |
and matching body temperature to mental alertness, et cetera, 00:13:06.620 |
it's pretty clear that exercising early in the day 00:13:10.020 |
not only biases us towards waking up earlier, 00:13:12.820 |
but that it also triggers the release of things 00:13:28.560 |
This can be very good because if you want to restrict 00:13:31.420 |
most of your focus learning to the early part of the day, 00:13:39.700 |
It tends to trigger activation of the go pathway. 00:13:47.800 |
early morning exercise within an hour of waking 00:13:50.480 |
and certainly no later than three hours after waking 00:13:53.440 |
will give you quote unquote more energy throughout the day. 00:13:57.120 |
So in kind of reviewing what I've set up until now, 00:14:04.780 |
and then I generally try and get exercise in the first hour 00:14:09.200 |
or ideally within the first three hours of waking up, 00:14:11.720 |
and then I'll move into a focused learning bout. 00:14:22.800 |
I typically eat my first meal right around midday, 00:14:29.320 |
In general, I rely on a low carbohydrate meal. 00:14:32.360 |
I'll eat meat or salad or some variation of that 00:14:39.200 |
I'm just going to continue to march through my day. 00:14:49.200 |
I start getting a little groggy, a little bit sleepy. 00:14:54.720 |
from work that requires a lot of duration path outcome, 00:14:58.040 |
really careful analysis and activation of the no-go pathway 00:15:04.160 |
I find I can do kind of typical more mundane tasks 00:15:08.120 |
because those tasks require less cognitive load 00:15:12.240 |
and they can be done more or less in and out of sequence. 00:15:18.760 |
And then typically around 4 p.m. or so, I do two things. 00:15:25.840 |
and then I always do a non-sleep deep rest protocol 00:15:31.000 |
This is sometimes a 10 minute yoga nidra type protocol 00:15:36.640 |
And I do that because for me by about 4.30 in the afternoon, 00:15:43.040 |
I personally find it a mistake to at that point 00:15:46.560 |
down a double espresso and charge really hard. 00:15:50.920 |
I end up really disrupting my sleep schedule. 00:15:52.980 |
I end up disrupting a lot of different things. 00:15:54.680 |
So for me, I do the non-sleep deep rest protocol. 00:15:59.800 |
feeling like I have another whole day second wind, 00:16:03.800 |
like I could just work, work, work, work, work. 00:16:10.640 |
that either involves linear analysis of something. 00:16:14.200 |
So maybe numerical work or I'm trying to learn something. 00:16:25.720 |
because I've come out of this non-sleep deep rest. 00:16:30.760 |
that I can sleep later that night really well. 00:16:33.280 |
And this tends to be more when I do creative type work. 00:16:37.120 |
Creativity is a very interesting state of mind 00:16:55.760 |
in a very relaxed way and kind of being playful 00:17:05.880 |
in which you take the idea or the design you've come up with 00:17:09.200 |
and you create something very robust and concrete. 00:17:12.640 |
And so creativity is really a two-part thing. 00:17:17.060 |
of actively exploring different configurations, 00:17:35.900 |
in that kind of clear, calm, and focused mode, 00:17:44.020 |
rely on substances to access creative states. 00:17:49.060 |
It's just not the drug for me for a variety of reasons. 00:17:54.100 |
It's not the substance for me for a variety of reasons. 00:17:57.340 |
The problem with using substances to access creativity 00:18:00.900 |
is that generally the substances that relax people 00:18:05.060 |
will allow them to get into that creative brainstorming mode 00:18:08.940 |
but not so good at the linear implementation mode. 00:18:13.140 |
So that afternoon block is when I try and access 00:18:22.340 |
For some of you, that state that favors creativity 00:18:25.300 |
and creative learning might be better in the morning. 00:18:29.880 |
For some of you, you're going to be late shifted. 00:18:34.900 |
generally we are good at linear implementation. 00:18:48.140 |
and we tend to be almost in a kind of sleepy mode. 00:19:00.300 |
And this brings about a question that I get all the time 00:19:07.460 |
On psychedelics, people report being able to smell colors 00:19:14.620 |
And that's because there's a lot of sensory blending. 00:19:19.260 |
that sensory blending itself is a creative process. 00:19:22.900 |
There's nothing creative about sensory blending. 00:19:29.020 |
is new ways of configuring things that lend themselves 00:19:32.220 |
to a bigger or greater or deeper or novel understanding 00:19:38.400 |
And just sensory blending is not going to accomplish that. 00:19:50.900 |
These are clinical studies done with a psychiatrist present 00:19:56.140 |
that can help people through depression, trauma, et cetera. 00:20:01.340 |
I don't take psychedelics to access creative states. 00:20:07.740 |
the important role of psychedelics might show up 00:20:11.620 |
I think that it may have these important roles 00:20:25.800 |
by having this period of non-linear exploration of concepts, 00:20:30.340 |
whatever it is I happen to be working on in the afternoon, 00:20:37.220 |
and then I'll revisit it the next day or even the next day 00:20:40.340 |
to see whether or not the work itself is ready 00:20:52.100 |
is that when we're very alert, do linear type of operations. 00:20:55.540 |
When we tend to be more sleepy and more relaxed, 00:20:58.260 |
that's when creative works can first be conceived, 00:21:02.020 |
but their implementation requires high levels of alertness. 00:21:06.340 |
Now that gets us more to the kind of late afternoon evening. 00:21:13.260 |
I'm a proponent of getting sunlight in the evening as well. 00:21:20.540 |
First of all, it makes sure that I don't get up too early, 00:21:23.300 |
that I'm not waking up at three or four in the morning 00:21:30.940 |
If you want to keep your schedule on a normal routine 00:21:37.380 |
and not have your circadian rhythms of sleep and wakefulness 00:21:43.840 |
in order to optimize learning and performance, 00:21:46.100 |
well, then you need to get morning light and evening light. 00:21:48.380 |
The morning light is going to advance my clock, 00:21:51.980 |
and the evening light is going to delay my clock a little bit 00:22:00.340 |
at more or less the same time each night and wake up 00:22:09.080 |
That's not some subjective thing that I tell myself, 00:22:19.180 |
and then I'll start to dim them for the evening 00:22:40.300 |
I'll just revisit a little bit of what I said before. 00:22:42.860 |
My evening meal tends to be more carbohydrate rich. 00:22:51.380 |
Remember, fasting and low carbohydrate states 00:22:55.780 |
Carbohydrate rich foods facilitate calmness and sleepiness. 00:23:03.180 |
I tend to achieve that state using carbohydrates 00:23:08.060 |
The next piece of scientific data that I'm going to describe 00:23:13.420 |
for sake of understanding how to optimize your brain 00:23:16.780 |
It also can help avoid a lot of anxiety issues. 00:23:20.120 |
The peak output of the circadian clock for wakefulness, 00:23:36.620 |
and body temperature is lowest right before waking. 00:23:39.720 |
Then as we wake up, our body temperature goes up 00:23:41.980 |
and into the afternoon, it continues to go up, up, up, up, 00:23:48.180 |
But there's a brief blip of release of peptides 00:23:53.000 |
and other substances from the sleep centers in the brain 00:23:56.980 |
that signals the peak of alertness and wakefulness 00:24:02.160 |
Now that's often the time when people start stressing 00:24:05.060 |
about the fact that they have something to do the next day 00:24:08.420 |
and it can cascade into a whole set of things. 00:24:10.440 |
I anticipate a peak in alertness and activity 00:24:16.780 |
I use that perhaps to get organized for the next day. 00:24:21.780 |
it's going to be very mundane tasks like cleaning 00:24:26.500 |
And that probably speaks to my cleaning abilities too. 00:24:29.500 |
I tend to go to sleep somewhere around 10, 30, 11. 00:24:31.540 |
And if all goes well, I stay asleep for four or five hours. 00:24:35.620 |
Typically it's three or four and then I wake up. 00:24:37.820 |
What it probably reflects is that the real time, 00:24:46.060 |
The word midnight was literally supposed to mean midnight. 00:24:55.740 |
and we've just deviated from it with artificial lights. 00:25:03.340 |
What it likely means is that you were supposed 00:25:31.760 |
And so I personally don't want to go to bed at 8 p.m. 00:25:34.540 |
A lot of good things happen between 8 p.m. and 11 p.m. 00:25:43.520 |
But as a consequence, I'm running out of melatonin. 00:25:55.520 |
and my mind is looping, I have a couple rules. 00:26:01.700 |
when I wake up in the middle of the night, any of it. 00:26:03.700 |
There's just nothing either for me terribly creative 00:26:20.020 |
at helping me turn off kind of looping thinking 00:26:22.900 |
in the middle of the night and fall back asleep. 00:26:29.980 |
certain types of tools for optimizing learning, 00:26:39.660 |
of creative type work in the afternoon, and that's it. 00:26:42.380 |
There are a lot of hours in between, of course, 00:26:48.420 |
not mundane tasks, but things that are kind of random. 00:26:52.540 |
Those are things like email or attending to Zoom meetings 00:27:03.800 |
where I'm trying to expand on the mental capacities 00:27:13.840 |
And so for many of you out there who are in school 00:27:18.380 |
the key is to slot in those brain optimization segments 00:27:21.800 |
of about 90 minutes, one or two, or maybe more per day. 00:27:25.400 |
You're trying to slot those in wherever you can 00:27:31.960 |
But you want to do that in an intelligent way 00:27:42.560 |
I think the way to look at any tool to modulate 00:27:46.800 |
or measure the nervous system is ask whether or not 00:27:54.080 |
whether or not it's gonna make you more alert or more calm, 00:28:01.360 |
I think the subjective reading of whether or not one 00:28:05.120 |
is alert or calm and whether or not that alertness 00:28:15.340 |
is the most valuable internal tool and recognition 00:28:20.840 |
But ultimately it's about tailoring that alertness 00:28:23.920 |
and calmness to the specific types of learning 00:28:26.240 |
and activities that you are going to do and perform. 00:28:29.160 |
And it's reciprocal, meaning some of those activities 00:28:34.960 |
your level of autonomic arousal and alertness. 00:28:40.520 |
Certain foods will tend to make you more sleepy. 00:28:42.560 |
And the volume of food and the timing of food 00:28:50.120 |
whether or not we're feeling well, performing well, 00:28:59.740 |
And to recognize that there are two bins of tools 00:29:03.120 |
for optimizing learning and brain performance. 00:29:14.360 |
For some of you, visualization might work terrifically well. 00:29:18.280 |
For some of you, one song might really wake you up 00:29:20.800 |
because of the associations you have with it. 00:29:24.760 |
it might repel me from the room 'cause I don't like it 00:29:29.200 |
But of course, volume is kind of a universal. 00:29:33.560 |
Soft music doesn't tend to wake them up quite as much. 00:29:36.640 |
So part of today is really getting you to think about 00:29:48.560 |
of every 24-hour cycle when you tend to be more awake 00:29:53.780 |
so you're not fighting an uphill battle to wake up 00:29:56.240 |
when you actually would want to be and should be sleepy 00:30:02.600 |
when you are naturally, you know, going to be most awake. 00:30:09.840 |
And then you start layering on the different protocols 00:30:15.740 |
that some people are just more go, go, go, go, go and no go. 00:30:23.360 |
and have a harder time getting into action in an activity. 00:30:29.240 |
that are more geared towards parasympathetic calm states. 00:30:36.400 |
and what particular goals you're trying to pursue. 00:30:39.280 |
As always, thank you for your interest in science.